Numidargistat dihydrochloride
Product Specifications
Target
Arginase
Related Pathways
Immunology/Inflammation
Purity
>99.99%
Bioactivity
Numidargistat dihydrochloride (CB-1158 dihydrochloride) is an orally active and highly effective arginase (ARG1) inhibitor, an immuno-oncology agent that inhibits TGF-?2-induced subcapsular cataract by reducing the proliferation of lens epithelial cells (LEC) and decreasing the expression of fibronectin, ?-SMA, collagen 1A1, and vimentin.
Smiles
O=C([C@@H](N)C)N1C[C@H](CCCB(O)O)[C@](N)(C(O)=O)C1.Cl.Cl
Molecular Formula
C11H24BCl2N3O5
Molecular Weight
360.04
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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