Calcimycin
Product Specifications
CAS Number
52665-69-7
Target
OXPHOS, Apoptosis, Antifungal, Autophagy, Antibacterial, Antibiotic
Related Pathways
Autophagy, Apoptosis, Microbiology/Virology
Purity
0.98
Bioactivity
Calcimycin (A-23187) is an ionophorous, polyether carboxylic antibiotic from Streptomyces chartreusensis. It binds and transports calcium and other divalent cations across membranes, uncouples oxidative phosphorylation, and inhibits ATPase of rat liver mitochondria. The substance is primarily used as a biochemical tool to study the role of divalent cations in various biological systems.
Smiles
CNc1ccc2oc(C[C@H]3OC4(CC[C@H]3C)O[C@H]([C@H](C)C(=O)c3ccc[nH]3)[C@H](C)C[C@H]4C)nc2c1C(O)=O
Molecular Formula
C29H37N3O6
Molecular Weight
523.62
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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