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BuChE-IN-TM-10

Product Specifications

CAS Number

2313524-95-5

Target

Cholinesterase (ChE), AChR

Related Pathways

Neuroscience

Purity

0.9954

Bioactivity

BuChE-IN-TM-10 (TM-10) is a potent inhibitor of butyrylcholinesterase (BuChE) with an IC50 of 8.9 nM. It effectively inhibits and disaggregates self-induced Aβ aggregation, exhibits significant antioxidant activity, and demonstrates substantial penetration through the blood-brain barrier (BBB), holding promise as a potential treatment for Alzheimer's disease.

Smiles

C(/C=C/C1=CC(OC)=C(OCCCCN(CC2=CC=CC=C2)CC)C=C1)(=O)N3CC=4C(CC3)=CC=CC4

Molecular Formula

C32H38N2O3

Molecular Weight

498.66

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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