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BPH-1358

Product Specifications

CAS Number

5352-53-4

Target

Antibacterial

Related Pathways

Microbiology/Virology

Purity

0.9974

Bioactivity

BPH-1358 (NSC-50460) (NSC-50460) is a potent human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS) inhibitor. With IC50s of 1.8 μM and 110 nM, respectively. And it is active against S. aureus in vitro (MIC ~250 ng/mL) [1][2].

Smiles

O=C(C1=CC=C(C2=CC=C(C(NC3=CC=CC(C4=NCCN4)=C3)=O)C=C2)C=C1)NC5=CC=CC(C6=NCCN6)=C5.[H]Cl.[H]Cl

Molecular Formula

C32H30Cl2N6O2

Molecular Weight

601.53

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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