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BMS-470539 dihydrochloride

Product Specifications

CAS Number

2341796-82-3

Target

Melanocortin Receptor

Related Pathways

Neuroscience, GPCR/G Protein

Purity

>99.99%

Bioactivity

BMS-470539 dihydrochloride is a selective and highly potent melanocortin 1 receptor (MC-1 R) agonist with anti-inflammatory activity. BMS-470539 attenuates oxidative stress and neuronal apoptosis via the MC1R/cAMP/PKA/Nurr1 signaling pathway in a neonatal hypoxia-ischemia rat model.

Smiles

CCCC(C1(C2=CC=CC=C2)CCN(CC1)C([C@H](NC([C@@H](N)CC3=CN=CN3C)=O)CC4=CC=C(C=C4)OC)=O)=O.Cl.Cl

Molecular Formula

C32H43Cl2N5O4

Molecular Weight

632.62

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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