BMS-1001 hydrochloride
Product Specifications
CAS Number
2113650-04-5
Target
PD-1/PD-L1
Related Pathways
Apoptosis|||Cell Cycle/Checkpoint|||Immunology/Inflammation
Purity
0.9957
Bioactivity
BMS-1001 hydrochloride is an orally active inhibitor of human PD-1/PD-L1 immune checkpoint with low-toxicity in cells.BMS-1001 alleviates the inhibitory effect of the soluble PD-L1 on the T-cell receptor-mediated activation of T-lymphocytes. BMS-1001 is capable of alleviating the PD-1/PD-L1 immune checkpoint-mediated exhaustion of Jurkat T-lymphocytes.
Smiles
Cl.Cc1cc(CN[C@H](CO)C(O)=O)c(OCc2cccc(c2)C#N)cc1OCc1cccc(c1C)-c1ccc2OCCOc2c1
Molecular Formula
C35H35ClN2O7
Molecular Weight
631.11
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Rabbit Polyclonal BCL9-2 Antibody [PE]](https://cdn.genprice.uk/genprice/uk/genprice3.webp)
350426-01 50 µL
Erbin (LAP2, Protein LAP2, Densin-180-like protein, Erbb2-interacting protein, ERBB2IP, ERBIN, KIAA1225)
Ask
View Details 
350426-02 200 µL
Erbin (LAP2, Protein LAP2, Densin-180-like protein, Erbb2-interacting protein, ERBB2IP, ERBIN, KIAA1225)
Ask
View Details 
GTR15218377 1 Vial
Lentiviral mouse Bhlhe41 shRNA (UAS) - Lentiviral mouse Bhlhe41 shRNA (UAS, RFP) plasmid
Ask
View Details