BLM-IN-1
Product Specifications
CAS Number
2056014-40-3
Target
Others|||Apoptosis
Related Pathways
Others|||Apoptosis
Bioactivity
BLM-IN-1 is a potent inhibitor of Bloom syndrome protein (BLM) with a KD of 1.81 ?M and IC50 of 0.95 ?M. It induces DNA damage response, apoptosis, and proliferation arrest in cancer cells.
Smiles
CCN(CC)CCCNc1cc2nc3\C(CCn3c(=O)c2cc1F)=C\c1ccc(cc1)C(C)C
Molecular Formula
C28H35FN4O
Molecular Weight
462.6
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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