Bisindolylmaleimide VIII acetate
Product Specifications
CAS Number
138516-31-1
Target
PKC, Apoptosis
Related Pathways
Cytoskeletal Signaling, Chromatin/Epigenetic, Apoptosis
Purity
0.9927
Bioactivity
Bisindolylmaleimide VIII acetate (Ro 31-7549 acetate) is a potent and selective PKC inhibitor (IC50: 158 nM for rat brain PKC) with IC50 values of 53, 195, 163, 213, and 175 nM for PKC-α, PKC-βI, PKC-βII, PKC-γ, and PKC-ε, respectively.
Smiles
CC(O)=O.Cn1cc(C2=C(C(=O)NC2=O)c2cn(CCCN)c3ccccc23)c2ccccc12
Molecular Formula
C26H26N4O4
Molecular Weight
458.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC940225-100 1x 100 µL
Major Vault Protein (MVP) (1032), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC400181-100 1x 100 µL
CD59 (heavy chain of Protectin) (BRA-10G), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680009-500 1x 500 µL
MART-1 / Melan-A (M2-7C10), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC881148-500 1x 500 µL
CD45RA (PTPRC/1148), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC682296-100 1x 100 µL
ACTH (Adrenocorticotrophic Hormone) (Pituitary Marker) (rCLIP/1407), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details