What is the catalog number for BI-4020?

The catalog number for BI-4020 is T10534.

What sizes are available for BI-4020?

BI-4020 is available in the following size(s): 1 mg, 5 mg, 1 mL - 10 mM (in DMSO), 10 mg, 25 mg, 50 mg, 100 mg, 200 mg.

How many pack sizes does BI-4020 come in?

BI-4020 is available in 8 different pack sizes.

BI-4020 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures BI-4020?

BI-4020 is manufactured by Molfinity.

What is the estimated delivery time for BI-4020?

Estimated delivery time for BI-4020 is approximately 10 business day(s), depending on your location.

BI-4020

Product Specifications

CAS Number

2664214-60-0

Target

EGFR

Related Pathways

JAK/STAT signaling, Tyrosine Kinase/Adaptors, Angiogenesis

Purity

>99.99%

Bioactivity

BI-4020 is a fourth-generation, orally active, and non-covalent inhibitor of EGFR tyrosine kinase. It exhibits activity against the triple mutant EGFR del19 T790M C797S variant (IC50=0.2 nM in BaF3 cell lines), the double mutant EGFR del19 T790M and primary mutant EGFR del19 (IC50=1 nM), and EGFR wt (IC50=190 nM) . BI-4020 also shows high kinome selectivity and good DMPK properties.