BI-2852
Product Specifications
CAS Number
2375482-51-0
Target
Ras|||Kras
Related Pathways
GPCR/G Protein|||MAPK
Purity
0.9898
Bioactivity
BI-2852 is a KRAS inhibitor targeting the switch I/II pocket (SI/II-pocket) with nanomolar affinity, leading to inhibition of downstream signaling and an antiproliferative effect in KRAS mutant cells.
Smiles
Cn1cnc(Cn2ccc3ccc(CNCc4[nH]c5ccccc5c4[C@H]4NC(=O)c5ccc(O)cc45)cc23)c1
Molecular Formula
C31H28N6O2
Molecular Weight
516.59
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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