BI-2852

Product Specifications

CAS Number

2375482-51-0

Target

Ras|||Kras

Related Pathways

GPCR/G Protein|||MAPK

Purity

0.9898

Bioactivity

BI-2852 is a KRAS inhibitor targeting the switch I/II pocket (SI/II-pocket) with nanomolar affinity, leading to inhibition of downstream signaling and an antiproliferative effect in KRAS mutant cells.

Smiles

Cn1cnc(Cn2ccc3ccc(CNCc4[nH]c5ccccc5c4[C@H]4NC(=O)c5ccc(O)cc45)cc23)c1

Molecular Formula

C31H28N6O2

Molecular Weight

516.59

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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