HIF1 agonist-1
HIF1 agonist-1 (compound F4) is a potent HIF1 agonist with an EC50 value of 0.9 μM. HIF1 agonist-1 can be used for researching anticancer[1].
Product Specifications
CAS Number
[333314-79-7]
UNSPSC
12352005
Hazard Statement
H315, H319
Target
HIF/HIF Prolyl-Hydroxylase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hif1-in-3.html
Purity
99.11
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(CCC1=CC=CC=C1)NC(C2=C(O)C3=NC=CC=C3C=C2)C4=CC=C(C=C4)OC
Molecular Formula
C26H24N2O3
Molecular Weight
412.48
Precautions
H315, H319
References & Citations
[1]Poloznikov AA, et al. Structure-activity relationship for branched oxyquinoline HIF activators: Effect of modifications to phenylacetamide "tail". Biochimie. 2017;133:74-79.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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