PROTAC Bcl2 degrader-1
Product Specifications
CAS Number
2378801-85-3
Target
Bcl-2 Family, PROTACs
Related Pathways
PROTAC, Apoptosis
Bioactivity
PROTAC Bcl2 degrader-1 is a PROTAC, which potently and selectively induces the degradation of Mcl-1 (IC50: 11.81 μM) and Bcl-2 (IC50: 4.94 μM; DC50: 3.0 μM) .
Smiles
O=C1NC(=O)C(N2C(=O)C=3C=CC=C(NCCOCCOCCNC(=O)CCCCC(=O)NCCN4C(=O)C5=CC=CC=6C(SC7=CC=C(Br)C=C7)=CC=C(C4=O)C56)C3C2=O)CC1
Molecular Formula
C45H45BrN6O10S
Molecular Weight
941.84
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
NBP2-55129-25ul 25 µL
Rabbit Polyclonal PD-ECGF/Thymidine Phosphorylase Antibody
Sign In for Pricing
View Details 
MBS6271405-01 0.1 mL
Acvr1, ID (Acvr1, Acvrlk2, Tgfb1, Activin receptor type-1, Activin receptor type I, Serine/threonine-protein kinase receptor R1, TGF-B superfamily receptor type I, TSK-7L) (MaxLight 550)
Sign In for Pricing
View Details MBS6271405-02 5x 0.1 mL
Acvr1, ID (Acvr1, Acvrlk2, Tgfb1, Activin receptor type-1, Activin receptor type I, Serine/threonine-protein kinase receptor R1, TGF-B superfamily receptor type I, TSK-7L) (MaxLight 550)
Sign In for Pricing
View Details ![Rabbit Polyclonal LAP1B Antibody [DyLight 550]](https://cdn.genprice.uk/genprice/uk/genprice4.webp)