PROTAC Bcl2 degrader-1
Product Specifications
CAS Number
2378801-85-3
Target
Bcl-2 Family, PROTACs
Related Pathways
PROTAC, Apoptosis
Bioactivity
PROTAC Bcl2 degrader-1 is a PROTAC, which potently and selectively induces the degradation of Mcl-1 (IC50: 11.81 μM) and Bcl-2 (IC50: 4.94 μM; DC50: 3.0 μM) .
Smiles
O=C1NC(=O)C(N2C(=O)C=3C=CC=C(NCCOCCOCCNC(=O)CCCCC(=O)NCCN4C(=O)C5=CC=CC=6C(SC7=CC=C(Br)C=C7)=CC=C(C4=O)C56)C3C2=O)CC1
Molecular Formula
C45H45BrN6O10S
Molecular Weight
941.84
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
K0638906 1.0 µg DNA
DUSP10 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1)
Sign In for Pricing
View Details 
MBS6150187-01 0.1 mL
TPM2 (TMSB, Tropomyosin beta Chain, Beta-tropomyosin, Tropomyosin-2) (FITC)
Sign In for Pricing
View Details MBS6150187-02 5x 0.1 mL
TPM2 (TMSB, Tropomyosin beta Chain, Beta-tropomyosin, Tropomyosin-2) (FITC)
Sign In for Pricing
View Details 