Lisaftoclax
Product Specifications
CAS Number
2180923-05-9
Target
Bcl-2 Family
Related Pathways
Apoptosis
Purity
0.9966
Bioactivity
Lisaftoclax (Bcl-2/Bcl-xl inhibitor 1) is an oral dual inhibitor of Bcl-2 and Bcl-xl, with IC50 values of 2 nM and 5.9 nM for Bcl-2 and Bcl-xl, respectively. Lisaftoclax is used to treat chronic lymphocytic leukemia (CLL) by inhibiting the action of the BCL-2 protein, which promotes the death of leukemia cells.
Smiles
[O-][N+](=O)c1cc(ccc1NC[C@H]1COCCO1)S(=O)(=O)NC(=O)c1ccc(cc1Oc1cnc2[nH]ccc2c1)N1CCN(CC2=C(CC3(CCC3)CC2)c2ccc(Cl)cc2)CC1
Molecular Formula
C45H48ClN7O8S
Molecular Weight
882.42
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15314776 1 Vial
Lentiviral human DEGS1 shRNA (UAS) - Lentiviral human DEGS1 shRNA (UAS, RFP) plasmid
Ask
View Details 
MBS6367626-01 0.2 mL
ZNF737, NT (ZNF737, ZNF102, Zinc finger protein 737, Zinc finger protein 102) (APC)
Ask
View Details MBS6367626-02 5x 0.2 mL
ZNF737, NT (ZNF737, ZNF102, Zinc finger protein 737, Zinc finger protein 102) (APC)
Ask
View Details 
