BAY-899
Product Specifications
CAS Number
2471967-92-5
Target
Others, GNRH Receptor
Related Pathways
Others, GPCR/G Protein
Bioactivity
BAY-899 is an orally active and selective antagonist of the luteinizing hormone receptor (LH-R), with IC50 values of 185 nM for human LH (hLH) and 46 nM for rat LH (rLH) . In vivo studies have shown that BAY-899 effectively reduces sex hormone levels[1].
Smiles
Fc1ccc(Oc2ncc(NC(=O)N3CCc4ncccc4[C@@H]3c3ccc(F)cc3)cn2)cc1
Molecular Formula
C25H19F2N5O2
Molecular Weight
459.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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