BAY-1816032
Product Specifications
CAS Number
1891087-61-8
Target
Others, Serine/threonin kinase
Related Pathways
Others, Metabolism, Cell Cycle/Checkpoint
Purity
0.9981
Bioactivity
BAY-1816032 is a benzimidazole budding inhibition relieved homolog protein 1 kinase (BUB1) inhibitor with IC50 of 0.7 nM and is orally active and abolishes nocodazole-induced Thr-120 phosphorylation of histone H2A, a major BUB1 target protein, in HeLa cells with IC50 of 29 nM.
Smiles
COc1cnccc1Nc1nc(ncc1OC)-c1nn(Cc2c(F)cc(OCCO)cc2F)c2ccccc12
Molecular Formula
C27H24F2N6O4
Molecular Weight
534.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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