A 83-01 sodium salt
Product Specifications
CAS Number
2828431-89-4
Target
ALK, TGF-beta/Smad
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, Stem Cells
Bioactivity
A 83-01 sodium salt is a potent inhibitor of TGF-β type I receptor ALK5 kinase, ALK4 and ALK7, with IC 50 s of 12 nM, 45 nM and 7.5 nM against the ALK5, ALK4 and ALK7 induced transcription, respectively [1].
Smiles
S=C(N1N=C(C2=NC(C)=CC=C2)C(C3=CC=NC4=CC=CC=C34)=C1)NC5=CC=CC=C5.[Na+]
Molecular Formula
C25H19N5NaS+
Molecular Weight
444.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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