Osimertinib dimesylate

2070014-82-1

EGFR

Angiogenesis|||Tyrosine Kinase/Adaptors|||JAK/STAT signaling

0.9981

Osimertinib dimesylate is an irreversible and mutant selective EGFR inhibitor (IC50s: 12 and 1 nM against EGFR L858R and EGFR L858R/T790M) .

CS(O)(=O)=O.CS(O)(=O)=O.COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cn(C)c2ccccc12

C30H41N7O8S2

691.82

Cool pack

-20°C