Golidocitinib
Product Specifications
CAS Number
2091134-68-6
Target
JAK
Related Pathways
Tyrosine Kinase/Adaptors, JAK/STAT signaling, Chromatin/Epigenetic, Angiogenesis, Stem Cells
Purity
>99.99%
Bioactivity
Golidocitinib (AZD4205) is a selective JAK1 inhibitor with an IC50 of 73 nM, while it weakly inhibits JAK2 and JAK3 with IC50 values greater than 14.7 μM and 30 μM, respectively.
Smiles
COc1nn(C)cc1Nc1nccc(n1)-c1c[nH]c2c(NC(=O)[C@@H](C)N3CCN(C)CC3)cccc12
Molecular Formula
C25H31N9O2
Molecular Weight
489.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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