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Golidocitinib

Product Specifications

CAS Number

2091134-68-6

Target

JAK

Related Pathways

Tyrosine Kinase/Adaptors, JAK/STAT signaling, Chromatin/Epigenetic, Angiogenesis, Stem Cells

Purity

>99.99%

Bioactivity

Golidocitinib (AZD4205) is a selective JAK1 inhibitor with an IC50 of 73 nM, while it weakly inhibits JAK2 and JAK3 with IC50 values greater than 14.7 μM and 30 μM, respectively.

Smiles

COc1nn(C)cc1Nc1nccc(n1)-c1c[nH]c2c(NC(=O)[C@@H](C)N3CCN(C)CC3)cccc12

Molecular Formula

C25H31N9O2

Molecular Weight

489.57

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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