AV-412

Product Specifications

CAS Number

451493-31-5

Target

EGFR

Related Pathways

Angiogenesis|||Tyrosine Kinase/Adaptors|||JAK/STAT signaling

Purity

0.9992

Bioactivity

AV-412 (MP412) is an EGFR inhibitor for EGFR, EGFR T790M, EGFR L858R, EGFR L858R/T790M, and ErbB2, with IC50 values of 0.75, 0.79, 0.5, 2.3, and 19 nM, respectively.

Smiles

Cc1ccc(cc1)S(O)(=O)=O.Cc1ccc(cc1)S(O)(=O)=O.CN1CCN(CC1)C(C)(C)C#Cc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)C=C

Molecular Formula

C41H44ClFN6O7S2

Molecular Weight

851.41

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MBS6491667-01 0.1 mL

PACSIN1, NT (Protein Kinase C And Casein Kinase Substrate In Neurons Protein 1, KIAA1379) (MaxLight 750)

Ask

View Details

MBS6491667-02 5x 0.1 mL

PACSIN1, NT (Protein Kinase C And Casein Kinase Substrate In Neurons Protein 1, KIAA1379) (MaxLight 750)

Ask

View Details

FAB94973A 0.1 mL

Mouse Monoclonal Adenosine A2aR/A2bR Antibody (826037) [Allophycocyanin]

Ask

View Details

E38QA8642 100 µL

WDSUB1 Antibody

Ask

View Details

C3445-26A 100 µL

Channel Kinase 1 (CHAK1, EC 2.7.11.1, FLJ20117, FLJ25718, LTRPC7, TRP-PLIK, TRPM7) (Not for Export EU)

Ask

View Details