What is the catalog number for Tuvusertib?

The catalog number for Tuvusertib is T10406.

What sizes are available for Tuvusertib?

Tuvusertib is available in the following size(s): 1 mg, 5 mg, 1 mL - 10 mM (in DMSO), 10 mg, 25 mg, 50 mg, 100 mg.

How many pack sizes does Tuvusertib come in?

Tuvusertib is available in 7 different pack sizes.

Is Tuvusertib in stock?

Tuvusertib is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Tuvusertib?

Tuvusertib is manufactured by Molfinity.

What is the estimated delivery time for Tuvusertib?

Estimated delivery time for Tuvusertib is approximately 10 business day(s), depending on your location.

Tuvusertib

Product Specifications

CAS Number

1613200-51-3

Target

ATM/ATR, Chk, Apoptosis

Related Pathways

DNA Damage/DNA Repair, PI3K/Akt/mTOR signaling, Apoptosis, Cell Cycle/Checkpoint

Purity

0.9966

Bioactivity

Tuvusertib (M1774) is an orally available ataxia telangiectasia and Rad3-related (ATR) kinase inhibitor (Ki< 1 μΜ) with selective and potentially antitumor activity.Tuvusertib selectively inhibits ATR activity and blocks downstream phosphorylation of serine/threonine protein kinase checkpoint kinase 1 (CHK1), thereby inhibits DNA damage checkpoint activation, disrupting DNA damage repair and inducing apoptosis in tumor cells.