AR-A 2

Product Specifications

CAS Number

220051-79-6

Target

Others|||5-HT Receptor

Related Pathways

GPCR/G Protein|||Neuroscience|||Others

Bioactivity

AR-A 2 is a selective 5-HT1B receptor antagonist with high affinity to guinea pig cortex 5-HT1B/1D and recombinant guinea pig 5-HT1B receptors (Ki: 0.24 and 0.47 nM), exhibiting a 10-fold lower affinity to guinea pig 5-HT1D receptor (Ki: 5 nM) .

Smiles

CC1=C2C(=C(C=C1)N3CCN(C)CC3)C[C@H](NC(=O)C4=CC=C(C=C4)N5CCOCC5)CC2

Molecular Formula

C27H36N4O2

Molecular Weight

448.6

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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