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APX-115

Product Specifications

CAS Number

1395946-75-4

Target

NADPH-oxidase, NADPH

Related Pathways

Metabolism, Immunology/Inflammation

Purity

0.9968

Bioactivity

APX-115 (Ewha-18278) (Ewha-18278) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox4) . APX-115 effectively prevents kidney injury.

Smiles

Cl.CCCc1c(O)n(nc1-c1ccccc1)-c1ccccn1

Molecular Formula

C17H18ClN3O

Molecular Weight

315.8

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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