APX-115
Product Specifications
CAS Number
1395946-75-4
Target
NADPH-oxidase, NADPH
Related Pathways
Metabolism, Immunology/Inflammation
Purity
0.9968
Bioactivity
APX-115 (Ewha-18278) (Ewha-18278) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox4) . APX-115 effectively prevents kidney injury.
Smiles
Cl.CCCc1c(O)n(nc1-c1ccccc1)-c1ccccn1
Molecular Formula
C17H18ClN3O
Molecular Weight
315.8
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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