AMG PERK 44
Product Specifications
CAS Number
1883548-84-2
Target
PERK, Autophagy
Related Pathways
Apoptosis, Autophagy
Purity
0.9981
Bioactivity
AMG PERK 44 is an orally active and selective PERK inhibitor (IC50: 6 nM) that induces autophagy. It also inhibits GCN2 (IC50: 7300 nM) and B-Raf (IC50 >1000 nM), making it useful for cancer research.
Smiles
Cl.Cc1ccc2cc(ccc2n1)-c1c(C)ccc(C(=O)c2c(-c3ccccc3)n(C)n(-c3ccccc3)c2=O)c1N
Molecular Formula
C34H29ClN4O2
Molecular Weight
561.07
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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