AMG PERK 44

Product Specifications

CAS Number

1883548-84-2

Target

PERK|||Autophagy

Related Pathways

Apoptosis|||Autophagy

Purity

0.9981

Bioactivity

AMG PERK 44 is an orally active and selective PERK inhibitor (IC50: 6 nM) that induces autophagy. It also inhibits GCN2 (IC50: 7300 nM) and B-Raf (IC50 >1000 nM), making it useful for cancer research.

Smiles

Cl.Cc1ccc2cc(ccc2n1)-c1c(C)ccc(C(=O)c2c(-c3ccccc3)n(C)n(-c3ccccc3)c2=O)c1N

Molecular Formula

C34H29ClN4O2

Molecular Weight

561.07

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

abx444818 100 µg

Ubiquitin Antibody

Ask

View Details

NBP2-50232C 0.1 mL

Mouse Monoclonal PALB2 Antibody (M41-P3F3) [DyLight 650]

Ask

View Details

SC327392 10 µg

TMEM217 (NM_001162900) Human Untagged Clone

Ask

View Details

MBS7147300 Inquire

Rabbit anti-Saccharomyces cerevisiae (strain 204508/S288c)(Baker's yeast) YJL225C Polyclonal Antibody

Ask

View Details

GL3741-5g 5 g

Piperaquine tetraphosphate tetrahydrate

Ask

View Details