AM-6494
Product Specifications
CAS Number
1874232-80-0
Target
Beta-Secretase, BACE
Related Pathways
Neuroscience
Bioactivity
AM-6494, a potent and orally active BACE1 inhibitor (IC50: 0.4 nM), exhibits in vivo selectivity over BACE2 (IC50: 18.6 nM) .
Smiles
C(OC)[C@]12[C@]([C@](C)(N=C(N)S1)C3=CC(NC(=O)C=4C=NC(OCC#C)=CN4)=CC(F)=C3F)(C2)[H]
Molecular Formula
C22H21F2N5O3S
Molecular Weight
473.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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