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ALK/ROS1-IN-1

Product Specifications

CAS Number

2365497-07-8

Target

ROS Kinase, ALK, Others

Related Pathways

Tyrosine Kinase/Adaptors, Angiogenesis, Others

Bioactivity

ALK/ROS1-IN-1 is a potent and selective anti-crizotinib-resistant ALK/ROS1 dual inhibitor (IC50s: 0.530 μM and 0.174 μM for ROS1 and ALK enzyme) .

Smiles

N(C1=CC(=CC=N1)N2C[C@@H](C(NCC3=CC=C(OC(F)(F)F)C=C3)=O)CCC2)C4=C(OC)C=C(C=C4)N5CCNCC5

Molecular Formula

C30H35F3N6O3

Molecular Weight

584.63

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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