AL 8697
Product Specifications
CAS Number
1057394-06-5
Target
P38 MAPK, Autophagy
Related Pathways
MAPK, Autophagy
Purity
0.9989
Bioactivity
AL 8697 is a selective p38α MAPK inhibitor (IC50 = 6 nM) with 14-fold selectivity over p38β (IC50 = 82 nM) and 300-fold selectivity over a panel of 91 kinases. AL 8697 has anti-inflammatory activity.
Smiles
Cc1c(F)cc(cc1-c1c(F)cn2c(nnc2c1F)C(C)(C)C)C(=O)NC1CC1
Molecular Formula
C21H21F3N4O
Molecular Weight
402.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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