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AHR antagonist 5

Product Specifications

CAS Number

2247953-39-3

Target

Aryl Hydrocarbon Receptor, Others

Related Pathways

Others, Immunology/Inflammation

Bioactivity

AHR antagonist 5 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist (example 39; IC50 < 0.5 μΜ) . It significantly inhibits tumor growth combined with checkpoint inhibitor anti-PD-1.

Smiles

Cl.Cl.Cl.CC(C)c1cnn2c(N[C@@H]3CCc4[nH]c5ccccc5c4C3)nc(nc12)-c1cncc(F)c1

Molecular Formula

C25H27Cl3FN7

Molecular Weight

550.89

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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