AHR antagonist 5
Product Specifications
CAS Number
2247953-39-3
Target
Aryl Hydrocarbon Receptor, Others
Related Pathways
Others, Immunology/Inflammation
Bioactivity
AHR antagonist 5 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist (example 39; IC50 < 0.5 μΜ) . It significantly inhibits tumor growth combined with checkpoint inhibitor anti-PD-1.
Smiles
Cl.Cl.Cl.CC(C)c1cnn2c(N[C@@H]3CCc4[nH]c5ccccc5c4C3)nc(nc12)-c1cncc(F)c1
Molecular Formula
C25H27Cl3FN7
Molecular Weight
550.89
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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