AGN 205327
Product Specifications
CAS Number
2070018-29-8
Target
Autophagy, Retinoid Receptor
Related Pathways
Autophagy, Metabolism
Purity
0.9971
Bioactivity
AGN 205327 is a potent synthetic agonist of retinoic acid receptors (RARs), with EC50 values of 3766 nM for RARα, 734 nM for RARβ, and 32 nM for RARγ, and AGN 205327 demonstrates no inhibitory activity against retinoid X receptors (RXRs), thereby exhibiting selective receptor subtype targeting that makes AGN 205327 an important tool for probing retinoid signaling pathways and investigating therapeutic applications of RAR activation.
Smiles
CC1(C)C=2C(=CC=C(C(=NO)C3=CC=4C(N3)=CC=C(C(O)=O)C4)C2)C(C)(C)CC1
Molecular Formula
C24H26N2O3
Molecular Weight
390.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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