AFP464 free base
Product Specifications
CAS Number
468719-52-0
Target
HIF/HIF Prolyl-Hydroxylase, HIF
Related Pathways
Metabolism, Angiogenesis, Chromatin/Epigenetic
Bioactivity
AFP464 (NSC710464) free base is an active HIF-1α inhibitor (IC50: 0.25 μM) and a potent aryl hydrocarbon receptor (AhR) activator.
Smiles
FC1=C2C(C(=O)C=C(O2)C3=CC(F)=C(NC([C@H](CCCCN)N)=O)C=C3)=C(N)C(F)=C1C
Molecular Formula
C22H23F3N4O3
Molecular Weight
448.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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