Aβ42-IN-1
Product Specifications
CAS Number
2582757-69-3
Target
Others, Gamma-secretase
Related Pathways
Neuroscience, Others, Stem Cells, Proteases/Proteasome
Bioactivity
Aβ42-IN-1, compound 1v, is a novel, potent and orally active γ-secretase modulator (GSM) . Aβ42-IN-1 potently reduced Aβ42 levels with an IC 50 value of 0.091 μM in cultured cells without inhibiting CYP3A4. Aβ42-IN-1 shows a sustained pharmacokinetic profile.
Smiles
O=C(C1=NC=C(C2=C(C)N=C3C(OCC4=CC=C(C5=CC=CC=C5)C=C4)=CC=CN32)C=C1)NCC.[H]Cl
Molecular Formula
C29H27ClN4O2
Molecular Weight
499
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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