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A-395

Product Specifications

CAS Number

2089148-72-9

Target

Histone Methyltransferase

Related Pathways

Chromatin/Epigenetic

Purity

0.9843

Bioactivity

A-395 is an antagonist of polycomb repressive complex 2 (PRC2) protein-protein interactions that potently inhibits the trimeric PRC2 complex (EZH2-EED-SUZ12, IC50: 18 nM) .

Smiles

CN(C)[C@H]1CN(C[C@@H]1c1ccc(cc1)N1CCN(CC1)S(C)(=O)=O)C1CCc2cccc(F)c12

Molecular Formula

C26H35FN4O2S

Molecular Weight

486.65

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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