A-395
Product Specifications
CAS Number
2089148-72-9
Target
Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic
Purity
0.9843
Bioactivity
A-395 is an antagonist of polycomb repressive complex 2 (PRC2) protein-protein interactions that potently inhibits the trimeric PRC2 complex (EZH2-EED-SUZ12, IC50: 18 nM) .
Smiles
CN(C)[C@H]1CN(C[C@@H]1c1ccc(cc1)N1CCN(CC1)S(C)(=O)=O)C1CCc2cccc(F)c12
Molecular Formula
C26H35FN4O2S
Molecular Weight
486.65
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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