7-Chlorokynurenic acid
Product Specifications
CAS Number
18000-24-3
Target
NMDAR, iGluR, GluR
Related Pathways
Neuroscience, Membrane transporter/Ion channel
Purity
0.9972
Bioactivity
7-Chlorokynurenic acid (7-chloro-4-hydroxy-2-carboxyquinoline) is an effecitve and selective antagonist of NMDA receptor with IC50 of 0.56 μM for the glycine B coagonist site. 7-Chlorokynurenic acid inhibits the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM and shows antinociceptive actions after neuraxial delivery.
Smiles
OC(=O)c1cc(O)c2ccc(Cl)cc2n1
Molecular Formula
C10H6ClNO3
Molecular Weight
223.61
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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