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(5Z,2E) -CU-3

Product Specifications

CAS Number

1815598-71-0

Target

Apoptosis

Related Pathways

Apoptosis

Purity

0.9902

Bioactivity

(5Z,2E) -CU-3 is a potent and highly selective inhibitor of the DGKα isozyme with an IC50 value of 0.6 μM, competing with ATP and exhibiting a Km value of 0.48 mM. It specifically targets the catalytic region of DGKα without affecting the regulatory region and has demonstrated antitumor and immunogenic effects by promoting cancer cell apoptosis and T cell activation.

Smiles

O=C1N(NS(=O)(=O)c2ccccc2)C(=S)S\C1=C/C=C/c1ccco1

Molecular Formula

C16H12N2O4S3

Molecular Weight

392.47

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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