(5Z,2E) -CU-3
Product Specifications
CAS Number
1815598-71-0
Target
Apoptosis
Related Pathways
Apoptosis
Purity
0.9902
Bioactivity
(5Z,2E) -CU-3 is a potent and highly selective inhibitor of the DGK? isozyme with an IC50 value of 0.6 ?M, competing with ATP and exhibiting a Km value of 0.48 mM. It specifically targets the catalytic region of DGK? without affecting the regulatory region and has demonstrated antitumor and immunogenic effects by promoting cancer cell apoptosis and T cell activation.
Smiles
O=C1N(NS(=O)(=O)c2ccccc2)C(=S)S\C1=C/C=C/c1ccco1
Molecular Formula
C16H12N2O4S3
Molecular Weight
392.47
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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