Regorafénib N-oxyde (M2)
Product Specifications
CAS Number
835621-11-9
Target
C-Kit, Drug Metabolite, PDGFR, VEGFR, c-RET, Raf
Related Pathways
MAPK, Apoptosis, Tyrosine Kinase/Adaptors, Angiogenesis, Metabolism
Purity
0.9948
Bioactivity
Regorafénib N-oxyde M2 is an active metabolite of Regorafenib, a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, RET, Kit, and Raf-1 (IC50s: 13/4.2/46, 1.5, 22, 7, and 2.5 nM) .
Smiles
CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)c(F)c2)cc[n+]1[O-]
Molecular Formula
C21H15ClF4N4O4
Molecular Weight
498.81
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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