Regorafénib N-oxyde (M2)

Product Specifications

CAS Number

835621-11-9

Target

C-Kit|||Drug Metabolite|||PDGFR|||VEGFR|||c-RET|||Raf

Related Pathways

MAPK|||Apoptosis|||Tyrosine Kinase/Adaptors|||Angiogenesis|||Metabolism

Purity

0.9948

Bioactivity

Regorafénib N-oxyde M2 is an active metabolite of Regorafenib, a multi-target inhibitor for VEGFR1/2/3, PDGFR?, RET, Kit, and Raf-1 (IC50s: 13/4.2/46, 1.5, 22, 7, and 2.5 nM) .

Smiles

CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)c(F)c2)cc[n+]1[O-]

Molecular Formula

C21H15ClF4N4O4

Molecular Weight

498.81

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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