4'-Ethynyl-2'-deoxyadenosine
Product Specifications
CAS Number
306305-07-7
Target
HIV Protease, Reverse Transcriptase, Others
Related Pathways
Microbiology/Virology, Others, Proteases/Proteasome
Bioactivity
4'-Ethynyl-2'-deoxyadenosine (4'-E-dA), a nucleoside reverse transcriptase (RT) inhibitor, demonstrates potent activity against drug-resistant HIV variants, with an EC50 of 98 nM in MT-4 cells for anti-HIV-1 activity.
Smiles
NC1=C2C(N(C=N2)[C@@H]3O[C@](C#C)(CO)[C@@H](O)C3)=NC=N1
Molecular Formula
C12H13N5O3
Molecular Weight
275.26
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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