4'-Ethynyl-2'-deoxyadenosine

Product Specifications

CAS Number

306305-07-7

Target

HIV Protease|||Reverse Transcriptase|||Others

Related Pathways

Microbiology/Virology|||Others|||Proteases/Proteasome

Bioactivity

4'-Ethynyl-2'-deoxyadenosine (4'-E-dA), a nucleoside reverse transcriptase (RT) inhibitor, demonstrates potent activity against drug-resistant HIV variants, with an EC50 of 98 nM in MT-4 cells for anti-HIV-1 activity.

Smiles

NC1=C2C(N(C=N2)[C@@H]3O[C@](C#C)(CO)[C@@H](O)C3)=NC=N1

Molecular Formula

C12H13N5O3

Molecular Weight

275.26

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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