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Voruciclib

Product Specifications

CAS Number

1000023-04-0

Target

CDK

Related Pathways

Cell Cycle/Checkpoint

Purity

0.9999

Bioactivity

Voruciclib is an orally active and selective CDK inhibitor (Ki: 0.626 nM-9.1 nM) that represses the expression of MCL-1 in multiple models of diffuse large B-cell lymphoma and effectively blocks CDK9, the transcriptional regulator of MCL-1.

Smiles

CN1CC[C@H]([C@@H]1CO)c1c(O)cc(O)c2c1oc(cc2=O)-c1ccc(cc1Cl)C(F)(F)F

Molecular Formula

C22H19ClF3NO5

Molecular Weight

469.84

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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