Voruciclib
Product Specifications
CAS Number
1000023-04-0
Target
CDK
Related Pathways
Cell Cycle/Checkpoint
Purity
0.9999
Bioactivity
Voruciclib is an orally active and selective CDK inhibitor (Ki: 0.626 nM-9.1 nM) that represses the expression of MCL-1 in multiple models of diffuse large B-cell lymphoma and effectively blocks CDK9, the transcriptional regulator of MCL-1.
Smiles
CN1CC[C@H]([C@@H]1CO)c1c(O)cc(O)c2c1oc(cc2=O)-c1ccc(cc1Cl)C(F)(F)F
Molecular Formula
C22H19ClF3NO5
Molecular Weight
469.84
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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