2',3'-cGAMP sodium
Product Specifications
CAS Number
2734858-36-5
Target
IFNAR, cGAS, STING, Endogenous Metabolite
Related Pathways
Immunology/Inflammation, Metabolism
Purity
0.9984
Bioactivity
2',3'-cGAMP sodium (2'-3'-cyclic GMP-AMP sodium) is a second messenger in cellular innate immunity, catalyzed by cGAMP synthase (cGAS) under DNA binding conditions. It binds to STING to form a dimer, inducing the production and expression of interferon-β and other cytokines.
Smiles
OC1([H])[C@](OP(OC[C@](O[C@@H](N2C3=NC=NC(N)=C3N=C2)[C@@H]4O)([H])[C@@]4([H])O5)(O[Na])=O)([H])[C@H](N6C(NC(N)=NC7=O)=C7N=C6)O[C@]1([H])COP5(O[Na])=O
Molecular Formula
C20H22N10Na2O13P2
Molecular Weight
718.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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