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Cyclosporin A

Product Specifications

CAS Number

59865-13-3

Target

Phosphatase, Complement System, Antibiotic

Related Pathways

Microbiology/Virology, Metabolism, Immunology/Inflammation

Purity

0.9999

Bioactivity

Cyclosporin A is a natural product and an active fungal metabolite, classified as a cyclic polypeptide immunosuppressant. It binds to cyclophilin and inhibits the activity of calcineurin (IC50 = 7 nM) as well as CD11a/CD18 adhesion molecules. It is commonly used to induce uremia models.

Smiles

[C@H]([C@@H](C/C=C/C)C)(O)[C@@]1(N(C)C(=O)[C@H]([C@@H](C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H]([C@H](C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C(=O)[C@H](CC)NC1=O)[H]

Molecular Formula

C62H111N11O12

Molecular Weight

1202.61

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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