Trimebutine

Product Specifications

CAS Number

39133-31-8

Target

Apoptosis|||Opioid Receptor|||Potassium Channel|||Calcium Channel|||IRAK|||NF-?B|||Akt|||JNK|||ERK|||TLR

Related Pathways

NF-?B|||GPCR/G Protein|||Immunology/Inflammation|||Membrane transporter/Ion channel|||MAPK|||Endocrinology/Hormones|||Cytoskeletal Signaling|||Apoptosis|||Metabolism|||PI3K/Akt/mTOR signaling|||Neuroscience

Purity

0.9986

Bioactivity

Trimebutine (Mebutin) is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal pain with antimuscarinic and weak mu-opioid agonist effects. It is marketed for the treatment of irritable bowel syndrome (IBS) and lower gastrointestinal tract motility disorders, with IBS being one of the most common multifactorial GI disorders. It is used to restore normal bowel function and is commonly present in pharmaceutical mixtures as trimebutine maleate salt form. Trimebutine is not an FDA-Approved/Clinical drug, but it is available in Canada and several other international countries.